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The Nandom District is one of the 254 Metropolitan, Municipal and District Assemblies (MMDAs) in Ghana, and forms part of the 11 of Municipalities and Districts in the Upper West Region.

It lies in the north western corner of the Upper West Region in Ghana between Long. 2°25 W and 2°45W and Lat. 10°20 and 11°00 and has its administrative capital at Nandom.

The total area of the District is put at 567.6 square km. This constitutes about 3.1% of the Region’s total land area. The District is estimated to have 84 communities with 95% of the inhabitants in the rural areas.  

It is bounded to the east and south by the Lambussie Karni District and Jirapa Municipal respectively and to the north and west by the Republic of Burkina Faso.

The population of the District according to 2010 population and housing census stands at 46,040 with 22,295 males and 23,745 females.