The Sekyere East District was created in 1988 by Legislative Instrument (L.I)1900 and is one of the 30 districts in the Ashanti Region of Ghana. It has Effiduase as the district capital. Located in the North-eastern part of the region, it lies approximately between Latitude 6° 45’ - 7° 32’ North and Longitude 0° 22’ west. The district shares common boundaries with some districts in Ashanti Region.
They include, Afigya Sekyere to the West - West, Sekyere West to the West, Ashanti Akim North to the South-East and Ejisu-Juaben to the South-West. It also shares boundaries with Sene and Atebubu Districts in the Brong Ahafo Region and Kwahu North District in the Eastern Region. Sekyere East District is the largest of all the twenty seven (27) Districts in Ashanti and covers a total land area of about 4,231.4sqkm.
The population of the district according to the 2010 Population and Housing Census stands at 62,172 with 29,511 males 32,661 females.