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Afadzato District is one of the twenty five (25) Municipalities and Districts in the Volta Region of Ghana. The District was curved out from Hohoe Municipal in the year 2012 and was inaugurated on the 28th June 2012 by then the President of the Republic of Ghana H.E. J.E.A Mills.

The Administrative capital of the District is Ve Golokwati. The District shares boundaries with Hohoe Municipal to the North, Kpando Municipal to the west, to the east with the Republic of Togo and to the south with Ho West District and South Dayi District respectively. The district was established by Legislative Instrument (L.I) 2079.

The population of the municipality according to 2010 population and housing census stands at 95,030 with 46,272 males and 48,758 females.