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Nanumba South District (NSD) which is situated about 211km southeast of the regional capital Tamale has Wulensi as the administrative capital and a total population of 64,577 projected from 2000 population and housing census.The district shares boundaries with Nanumba North district to the north and west, Zabzugu District and the Republic of Togo to the east, Nkwanta South district to the south-east, the East Gonja district to the south-west and Kpandai district to the south. The district was established by Legislative Instrument (L.I) 1763. It has one hundred and nineteen (119) communities with four hundred and thirteen nine (413) community- based surveillance (CBS) volunteers and Community- based agents (CBA) who assist in carrying out health activities at the community level.The district has an estimated land area of about 1.300sqkm. It is further divided into four (4) health sub-districts namely: Lugni, Nakpayili, Pudua, Wulensi.
The people who are mostly peasant farmers and petty traders are generally found in small settlements scattered all over the district with populations between 200-1000 people. Distances between settlements/villages are long and difficult to reach because of poor road network and this is worse during the raining season when streams spring up almost everywhere. This negatively impacts on health delivery in the district. The district is occupied by two major ethnic groups, namely the Nanumbas and Konkonbas and a few Basares and other minority tribes with the Nanumbas forming the dominant ethnic group. Therefore major languages spoken are Nanumba and Konkomba.
The population of the district according to 2010 population and housing census stands at 93,464 with 46,776 males and 46,688 females.